Speaker
Cornelius Roemer
(University of Basel and SIB)
Description
Five years since the start of the pandemic, SARS-CoV-2 remains a leading cause of acute respiratory infections, despite most people having been infected at least once. Unprecedented levels of global genomic surveillance provide a rich basis for understanding how SARS-CoV-2 variants continue to evolve in the post-Omicron era, a critical topic for vaccine strain updates.
Using insights gained during three years of maintaining the Pango lineage system, I will describe the major patterns of variant evolution and how they have changed over time. I will also outline how we adapted Nextclade to efficiently make accurate lineage calls by using algorithmically constructed founder sequences.
| Expedited Notification | No thanks, I do not require Expedited Notification |
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Primary author
Cornelius Roemer
(University of Basel and SIB)
Co-author
Prof.
Richard Neher
(University of Basel and SIB)