Conveners
Transmission Dynamics & Clusters
- Angela McLaughlin (Dalhousie University)
- Noémie Lefrancq (ETH Zürich)
Most pathogen phylodynamics analyses are done in the context of unclear sampling denominators, low sampling density, and limited participant meta-data. In contrast, the Rakai Health Sciences Program has embedded deep-sequencing of all HIV-viremic individuals into population-based surveillance, enabling linkage of genomic data with a large range of sociodemographic and behavioural covariates....
Cluster and source attribution methodologies in genomic epidemiology are primarily used to identify pairs or groups of infected individuals sharing close proximity in the chain of transmission. It is generally overlooked that these methodologies also identify some number of individuals who are not linked to anyone else, and that the number of these is informative. If one is to take a random...
BACKGROUND:
Transgender (trans) people are frequently marginalized in HIV surveillance. Trans women are often grouped with gay and bisexual men (GBM), while trans men and non-binary people are commonly excluded. This can perpetuate inequity in prevention and care.
METHODS:
We analyzed clinical data from 15,299 individuals living with HIV in British Columbia (BC) Canada (1999-2022)....
Mpox denotes a viral zoonosis caused by the Orthopoxvirus monkeypox (MPXV), which is endemic in West and Central Africa. In spring 2022, notable outbreaks of MPXV clade IIb were recorded in several high-income countries, predominantly affecting men who have sex with men (MSM). At the peak of the outbreak, over 200 new Mpox cases per week were reported in Berlin, which constitutes one of the...
